NAD+

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells. It is critical for metabolism, mitochondrial function, and cellular energy production. NOT a peptide. Precursors like NMN and NR are more commonly used for supplementation.

PubMed results: 45,822 · Human studies: 14,492 · Animal studies: 29,137

Ranges reflect protocols studied in published research and animal-model extrapolation. Presented for research purposes only, not a recommendation or instruction for human use.

• Intravenous — standard range 250-1000 mg, Weekly

Unknown (low confidence)

• NCT02425904 — Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related Disorders (PHASE2), status: ACTIVE_NOT_RECRUITING. Indications: Langerhans Cell Histiocytosis
• NCT04158934 — A Long-term Study of ADYNOVI/ADYNOVATE in Participants With Haemophilia A, status: ACTIVE_NOT_RECRUITING. Indications: Hemophilia A
• NCT06590844 — "cindilizumab + Bevacizumab + Coenzyme I for Injection" in Unresectable Hepatocellular Carcinoma (PHASE4), status: ACTIVE_NOT_RECRUITING. Indications: Unresectable Hepatocellular Carcinoma
• NCT04257409 — Musculoskeletal Changes After Physiotherapeutic Intervention in Podiatric Subjects (NA), status: UNKNOWN. Indications: Prevention of Diabetic Foot
• NCT02143687 — Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise Performance (PHASE4), status: COMPLETED. Indications: Precapillary Pulmonary Hypertension, Interstitial Lung Disease
• NCT02164864 — Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI) (PHASE3), status: COMPLETED. Indications: Atrial Fibrillation, Percutaneous Coronary Intervention
• NCT06882096 — Tracing the Metabolic Flux of Orally Administered NAD+ Precursors (PHASE1), status: RECRUITING. Indications: Healthy Adults
• NCT02477501 — Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section (PHASE4), status: COMPLETED. Indications: Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
• NCT07119190 — A Perioperative Comprehensive Diagnosis and Treatment System for Lung Cancer in the Era of Neoadjuvant Immunotherapy, status: NOT_YET_RECRUITING. Indications: Non-Small Cell Lung Cancer
• NCT00835978 — Axitinib (AG-013736) With Or Without Dose Titration (Increase) In Patients With Kidney Cancer (PHASE2), status: COMPLETED. Indications: Carcinoma, Renal Cell
• NCT06313203 — HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT) (PHASE2), status: RECRUITING. Indications: Intrahepatic Cholangiocarcinoma, Chemotherapy Effect
• NCT03371082 — Gan & Lee Insulin Glargine Target Type (1) Evaluating Research (PHASE3), status: COMPLETED. Indications: Diabetes Mellitus, Type 1
• NCT01768520 — Evaluation of the Efficacy and Safety of Entelon Tab. 150mg in Patients With Osteoarthritis of Knee (PHASE3), status: COMPLETED. Indications: Knee Osteoarthritis
• NCT04948996 — Treatment of Depression Using a Mobile Application in the Dominican Republic (NA), status: TERMINATED. Indications: Depression Mild, Depression Moderate
• NCT02495727 — Two Weeks of Reduced Activity and Skeletal Muscle Health in Older Men (NA), status: COMPLETED. Indications: Muscular Atrophy
• NCT01813370 — A Registry for Patients Treated on the Clinical Trial TAX 3503, status: COMPLETED. Indications: Prostate Cancer
• NCT04880642 — A Trial to Investigate Recovery From COVID-19 With C21 in Adult Subjects (PHASE3), status: COMPLETED. Indications: COVID-19
• NCT02523040 — Lenalidomide for Adult Histiocyte Disorders (PHASE2), status: ACTIVE_NOT_RECRUITING. Indications: Langerhans Cell Histiocytosis (LCH), Histiocytoses Erdheim-chester Disease, Histiocytic Sarcoma (HS)
• NCT06776510 — A Clinical Study of NAD in the Treatment of Immune Thrombocytopenia (PHASE1 / PHASE2), status: RECRUITING. Indications: Immune Thrombocytopenia, Treatment
• NCT02114788 — Interactive Sections Of An Internet-Based Intervention Increase Patient Empowerment: A Study With Chronic Back Pain Patients, status: COMPLETED. Indications: Group 1 (Control): Access to a Static Version of the Website Containing Only Static Features (i.e. Library, First Aid, and FAQ), Group2 (Intervention) Access to an Interactive Version of the Website Containing Both Static and Interactive Features