PROTOCOLprotocol_logs·May 6, 2026 at 07:17 PM
Cagrilintide standalone protocol (pre-CagriSema research)
P
PubMedDaily
ADVANCED · P2
2
Standalone cagrilintide before the semaglutide combination. The Phase 2 standalone data showed ~10.8% weight reduction at 26 weeks, which is the cagrilintide-alone effect.
Protocol mirrors the Phase 2 dose escalation. Useful as a baseline before combination protocols.
PROTOCOL PARAMETERS
| Compound | Dose | Frequency | Route |
|---|---|---|---|
| Cagrilintide | 0.3mg → 0.6mg → 1.2mg → 2.4mg | Weekly | SubQ |
Duration:16 weeks (4 weeks per dose level)
Goals:Amylin receptor agonism baseline characterization
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