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Four weeks in on tirzepatide weekly. Standard escalation (2.5mg → 5mg week 5). Fasting glucose down 12 points. Triglycerides down 28%. Weight down 4.2%.
GI side effects manageable. Nausea peaked at week 1, basically gone by week 3.
Baseline biomarkers were good but not exceptional. The metabolic response is in line with the SURMOUNT-1 average for early weeks.
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