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Boehringer-Zealand's GLP-1/glucagon dual agonist. Mechanistically similar to mazdutide but different molecule. Their MASH trial readouts have been interesting — substantial liver fat reductions.
Feels like the dual GLP-1/glucagon class is getting crowded fast. Reta is winning the obesity race because of triple agonism but for MASH specifically the dual approaches might have advantages.
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