PROTOCOLprotocol_logs·May 7, 2026 at 08:01 AM

Tesamorelin + Ipamorelin combination GHRH/GHS-R framework

H
HRVdaily
RESEARCHER · P1
25

Tesamorelin produces the GHRH pathway activation, ipamorelin produces ghrelin receptor activation. Combining both pathways approximates the synergistic GH release documented by Bowers and colleagues for combination protocols.

Different half-lives mean tesamorelin needs the larger frequency.

PROTOCOL PARAMETERS
CompoundDoseFrequencyRoute
Tesamorelin1mgDailySubQ
Ipamorelin200mcgDaily, eveningSubQ
Duration:12 weeks
Goals:Combined GHRH + GHS-R activation per Bowers synergy literature

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