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Tesamorelin produces the GHRH pathway activation, ipamorelin produces ghrelin receptor activation. Combining both pathways approximates the synergistic GH release documented by Bowers and colleagues for combination protocols.
Different half-lives mean tesamorelin needs the larger frequency.
| Compound | Dose | Frequency | Route |
|---|---|---|---|
| Tesamorelin | 1mg | Daily | SubQ |
| Ipamorelin | 200mcg | Daily, evening | SubQ |
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