Tirz dose escalation — why is everyone scared of going past 10mg

Just curious about the community's experience. The SURMOUNT data showed monotonic dose-response up to 15mg with the largest effects at 15. But anecdotally a lot of researchers seem to stay at 10 or even 7.5.

Is it the GI burden? The plateau hypothesis? Or is 10mg producing 90% of the effect for most people and the marginal 5mg isn't worth the side effect cost?