PROTOCOLprotocol_logs·May 6, 2026 at 06:34 AM
Tirz aggressive titration — abbreviated escalation
Q
QuantifiedSelf
ADVANCED · P2
1
For research subjects with prior GLP-1 exposure who tolerated semaglutide well. Faster escalation than the standard SURMOUNT protocol because baseline GI tolerance is already established.
Not for first-time GLP-1 research. The slow titration matters for new exposure.
PROTOCOL PARAMETERS
| Compound | Dose | Frequency | Route |
|---|---|---|---|
| Tirzepatide | 5mg → 10mg → 15mg | Weekly | SubQ |
Duration:12 weeks (4 weeks per dose level)
Goals:Accelerated dose-response research in GLP-1 experienced subjects
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