Humanin

Humanin is a 24-amino-acid peptide encoded by mitochondrial DNA. It was discovered as a protective factor against Alzheimer's disease amyloid toxicity. It has cytoprotective, anti-apoptotic, and metabolic effects.

PubMed results: 512 · Human studies: 298 · Animal studies: 433

• NCT05506228 — How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery., status: RECRUITING. Indications: Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
• NCT06125249 — Humanin's Value for Early Diagnosis and Short-term Prognosis in Patients With AKI After Heart Transplantation, status: UNKNOWN. Indications: Acute Kidney Injury, Heart Transplant Surgery
• NCT06105229 — Clinical Value of Plasma Humanin in Acute Kidney Injury, status: UNKNOWN. Indications: Acute Kidney Injury
• NCT04104958 — IVF Outcome in Polycystic Ovary Syndrome Patients, status: UNKNOWN. Indications: Polycystic Ovary Syndrome
• NCT03431844 — Humanin Isoforms in Cardiac Muscle and Blood Plasma and Major Complications After Cardiac Operation, status: COMPLETED. Indications: Myocardial Ischemia, Coronary Artery Bypass Surgery
• NCT07438002 — Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment (NA), status: RECRUITING. Indications: Chronic Kidney Disease